Transport for Greater Manchester and Rochdale Council are consulting on proposals to improve the Manchester New Road route between Mount Road and Mossway.
The proposals include improvements to an existing pedestrian crossing point at Kingsway, a new northbound bus lane where the M60 slip road joins Manchester New Road, and a new southbound bus lane at Alkrington Green.
Use of the bus lanes will be limited to buses, cycles, hackney carriages and emergency vehicles.
A five-week long consultation launched on Monday 25 March.
Over 2,000 leaflets are being sent to people in the area and will be available from community outlets. An event will also be held at Middleton Bus Station.
The plans are part of a wider £54m bus priority package, which aims to improve links to employment, education, and healthcare facilities such as the universities and hospital sites on Oxford Road to the south of the city centre.
The latest proposals are in addition to improvements along Rochdale Road, which cover the route from Blackley, Harpurhey and Collyhurst, to Shudehill Interchange in Manchester city centre. Public consultation for this section of the route took place in October 2012.
Peter Boulton, TfGM's head of programme management services, said: "We have listened to feedback on previous plans and revised our scheme. We now want to hear what people think of the new proposals to help us finalise the details. I encourage everyone to find out more and take the opportunity to have their say."
TfGM and Rochdale Council officers will be at Middleton Bus Station on Tuesday 16 April, between 2pm and 7pm, to discuss the plans