Ben Roberts, investment director and head of Kenmore's Manchester office since it opened in 2002, is leaving to go it alone.
In an email sent to contacts today, Roberts, who joined Kenmore from Richard Ellis, said: "After six and a half very enjoyable years running Kenmore's Manchester office I have decided to leave the company and pursue my own interests."
He added: "I hope to be able to announce what I plan to do in the near future."
Kenmore's Manchester office will be run by Mark Robinson. The group recently announced six job losses including staff in Leeds.
The firm's schemes in the North West include offices at Jackson House in Sale and Royal London House in Manchester city centre.