The thriving British trainer manufacturer has agreed a lease for the 30,666 sq ft Appleton House at Birchwood Point Business Park with landlord Aviva.
New Balance took a 10-year lease on the building and was represented by CBRE. Savills acted for the landlord.
New Balance will relocate from its current UK head office in Centre Park, Warrington. The company also has a shoe production factory in Flimby, Cumbria where it employs 210 people.
CBRE's building consultancy team has been appointed to design and manage the fit-out of Appleton House and work is due to start on site this month in order for the teams to move into the building in September.
Michelle Rothwell, senior surveyor of office agency at CBRE in Manchester, said: "We conducted an extensive search on behalf of New Balance and Appleton House matched their requirement for a stand-alone headquarter building with potential to create the modern working environment they are seeking to reflect the nature of their brand."
Julian Cobourne, asset manager at Aviva, said: "Aviva Investors is committed to providing high quality office space and we set out with a clear strategy for Appleton House. Having undertaken a significant refurbishment, it is satisfying to be attracting a tenant of the profile and quality of New Balance. This location remains highly attractive for office occupiers and this letting is testament to the investment in the building and the high quality refurbishment."