The airport will operate from a single terminal in the face of reduced passenger numbers.
The Government has advised against non-essential travel and many countries are closing their borders as the world attempts to contain the coronavirus outbreak.
These measures have resulted in a sharp drop in the number of people taking flights and as of Wednesday next week, Manchester Airport will close terminals two and three in a response to this.
A statement from Manchester Airport Group said: “Like all airports across the world, Manchester Airport has experienced a significant fall in passenger volumes as a result of the Covid-19 pandemic.
“Given this reduction in departing and arriving flights, and the likelihood traffic will decline further, we have taken the decision to work towards operating from a single terminal.
“This will happen on Wednesday 25 March and all flights that were due to depart from Terminal Two and Terminal Three, will now do so from Terminal One.”