Richard Rogers' cancer respite facility, Maggie's Centre in West London, triumphed at the RIBA Stirling Prize, with the Liverpool One masterplan by BDP among the runners-up.
BDP was the first practice to be nominated for a masterplan rather than a building in the most important competition in British architecture.
Maggie's Centre was commissioned by Charles Jencks, whose wife Maggie died of cancer 12 years ago. Accepting the award at a televised ceremony broadcast live on Saturday evening, Rogers said: "The one person missing here is Maggie. She will certainly be the person I am thinking of."
RIBA judges said Liverpool One was a "vibrant and economically successful retail, leisure and mixed-use quarter. The masterplan co-ordinates and manages the development of 42 acres of rundown land. Achieving implementation within nine years is a triumph of skill and commitment."
- Liverpool One won the RICS Regeneration Award for 2009 at a ceremony on Thursday. Gorton Monastery in Manchester was commended in the Building Conservation category.