The governing body for Rugby League in the UK and Super League (Europe) have relocated their commercial, marketing and media functions to refurbished offices at Peel's Quay West in Trafford Wharf.
Blake Solly, Super League general manager said: "This is an exciting move that will raise the profile of Rugby League and better enable the sport to meet its commercial objectives.
"The relocation is in line with our established strategy of serving all our stakeholders nationally from three sites in Leeds, London and MediaCityUK.
"The presence of our World Cup team at MediaCityUK was an important factor in the success of the tournament and its relocation is a clear, natural and logical development."
The RFL and Super League's relocation to 4,000 sq ft of offices in Quay West on the banks of the Manchester Ship Canal follows the success of the RFL's residency at The Greenhouse in MediaCityUK which housed the administrative headquarters of Rugby League World Cup 2013, the most successful international tournament in the sport's history.
The RFL's marketing, commercial, communications, digital media, ticketing and events departments now operate from the newly refurbished office accommodation in Quay West as well as the Super League's recently appointed General Manager Blake Solly and the RFL's North West development teams.
Stephen Wild, managing director of MediaCityUK said: "The RFL is the first major sporting organisation to make MediaCityUK its home. The combination of its close proximity to key broadcast sports outlets and a host of creative and media talent will undoubtedly help raise the profile of this fantastic sport."