Potter Logistics has taken an 87,650 sq ft facility at Charleywood Point in Knowsley Industrial Park on a 10-year lease.
The warehouse is owned by Threadneedle Investments and was formerly occupied by DHL. Potter will use the unit as a distribution centre on behalf of its client Elanco, the animal health division of Lilly.
The facility has been let at a headline rent of £3.75/sq ft.
B8 Real Estate and JLL acted on behalf of Threadneedle, while Fox Lloyd Jones represented Potter.
Matthew Lamb, managing director of Potter Logistics, said: "This new facility is the culmination of a year's hard work from our staff and Elanco. The new distribution centre gives clients the opportunity to store products in the North West at a well-connected industrial park with rail links."
Steve Johnson, partner of B8 Real Estate, said: "This latest letting at Knowsley reinforces the improving logistics market where we are seeing increased demand for good quality units in the 50,000 sq ft to 150,000 sq ft size range, with Merseyside the recent beneficiary of several large lettings."