Lancaster City Council has given planning approval for a 40,000 sq ft Sainsbury's store to be built at Christie Park, current home of Morecambe Football Club.
The supermarket giant announced in January this year that it would acquire the Christie Park stadium from Morecambe FC in 2010.
Unusually, the sale was not conditional upon Sainsbury's securing planning permission.
A delighted Andrew Watt, at MAZE Planning, Morecambe FC's planning adviser, said: "This is great news for the partnerships that has been forged between Sainsbury and the Football Club. At a time of continued difficulty for the UK economy the people of Morecambe are set to benefit hugely from access to modern sports and retail facilities, together with hundreds of jobs created during construction and at the completed schemes.
"We're hoping for a quick response to the application from the Secretary of State so that Sainsbury's can set a construction programme which gets them on site in June 2010, to coincide with the Football Club's exit from Christie Park."
Last year, Morecambe FC won planning consent to build a new ground as part of a mixed-use scheme with hotel and restaurants in Westgate.
The club is on site at Westgate constructing its new stadium, which will be ready to host games in the 2010/2011 football season.
Manchester-based Redhouse is project managing the site development works. The new stadium complex will include community pitches, a hotel and restaurants.
Turley Associates' Manchester office is advising Sainsbury's on planning at Christie Park.