The 3.5m sq ft plot of land around the intu Trafford Centre and other tourist attractions such as Airkix and Chill Factore is set to be named Trafford City by owner Peel.
Trafford City will encompass retail, leisure and office space that includes Event City and occupiers such as Play Factore, David Lloyd, DW Sports and office tenants Reckitts Benckiser, Capita, Spie and Travel Counsellors.
There are currently 16,500 people employed on the site, which Peel said attracts 44 million visitors a year.
According to Peel, there are plans to double the current number of 750 hotel bedrooms across Trafford City as part of a masterplan for the area.
The announcement comes as work is nearing completion on the £45m Western Gateway infrastructure scheme that will bring an additional road link into Trafford City from the A57 in Salford to Trafford Boulevard and Junction 10 of the M60.
The final go-ahead for the Metrolink line between Trafford City and Manchester is also expected to be given shortly.
Mark Whittaker, group property director for The Peel Group, said: “From as far back as 20 years, it has been Peel’s vision to create an unrivalled mixed use destination in the North West. It started with the opening of intu Trafford Centre in 1998 and has evolved over the years to become a destination not just for retailing but also for leisure, work and living accommodation.
“The Trafford City brand not only gives an all-encompassing name to the entire area that will become recognised both regionally and also on a national level. It will help to unify the attractions – creating a powerful collective offering to consumer and commercial customers alike.”