Pure Gym has signed a 15-year lease on 19,000 sq ft at Winwick Quay Business Park in Warrington.
The 24-hour gym operator has taken a former manufacturing unit at Chetham Court, which also houses leisure occupiers LA Bowl and The Jungle.
Landlord Winwick Quay LLP successfully gained a change of use consent to secure the deal.
Ian Murray from Riddell TPS, asset manager of the park, said: "The letting to Pure Gym is another piece of our jigsaw and helps increase leisure usage on Chetham Court. The external elevations of the building will be improved and Pure Gym will definitely take advantage of the prime location on the A49 along with the pull of the other leisure occupiers and the free car parking.
"The concept of low monthly fees, no contract, hi-tech equipment and 24 hour access will be a real benefit to the local residents and workers of Warrington."
Joint letting agents for the estate are Riddell TPS and Colliers International.
The gym will open in early February 2011 once fit out works have been completed.