Lancashire County Council has awarded Costain with a contract to build a major link road between Torrisholme and Halton.
The Early Contractor Involvement contract is worth £139m and will link the A589 Morecambe Road, near Torrisholme, to a fully remodelled junction 34 on the M6 motorway near Halton.
As well as developing the design and construction of the road, Costain is also required to support the council in taking the scheme through the statutory process, including a public inquiry.
The route is a 4.8km long two-lane dual carriageway. Around 20 major structures will need to be built including bridges over the West Coast Mainline railway, Lancaster Canal and the River Lune.
Andrew Wyllie, chief executive of Costain, said: "We are delighted to have been awarded this ECI contract which further underlines our position as a market leader in the construction and maintenance of highways in the UK."