Construction services company Jacobs has taken a 10-year lease on 23,526 sq ft of space at Ask Property Developments' Number One First Street in Manchester.
Ask was advised on the deal by Savills and CBRE. Vail Williams advised Jacobs.
Number One First Street was previously occupied by Manchester City Council and has 135,000 sq ft of space available. It stands adjacent to the First Street North development.
Jamie Hills, development executive at Ask, said: "Jacobs will arrive at First Street at a very exciting time as we have commenced construction of First Street North.
"They will be part of a new exciting and vibrant, mixed use environment anchored by HOME, the new venue for the merged Manchester arts organisations, Cornerhouse and Library Theatre Company.
"The development also comprises a four star Melia hotel, 700 space multi storey car park, nine new restaurant/café units, student accommodation and a new public square.
"When completed, the complex will total one million sq ft of offices, leisure, retail and residential."