The Thai Tapas chain will set up shop within the former Carluccio’s unit in Spinningfields.
Giggling Squid has more than 40 restaurants nationally but they are concentrated mainly around the South East.
A licensing application to Manchester City Council requests permission to operate out of the former Carluccio’s unit at 3 Hardman Square.
Carluccio’s collapsed into administration at the beginning of the pandemic but was bought out by Boparean Restaurant Group in May 2020.
The Spinningfields restaurant was one of 41 BRG closed for good when it took over.
Giggling Squid, founded by Pranee Laurillard in 2002, wants to increase the capacity of the venue, adding 59 covers through the creation of a mezzanine level.
Giggling Squid’s Spinningfields move follows news of another new arrival to Manchester’s business district Sexy Fish, the high-end Asian restaurant, will take over the former Armani store facing Deansgate, as first revealed by Place North West in August.