The 42,000 sq ft building on Castle Street in Macclesfield has been put on the market by parent Nationwide Building Society.
Colliers International has been instructed to sell 36 Castle Street on a freehold basis although consideration would be given to a leasehold deal.
The building still retains its directors' suite and boardrooms behind a period facade. There is also secure parking for 15 cars.
Cheshire Building Society, founded in Macclesfield in 1870, is vacating the premises following its acquisition by Nationwide Building Society in December 2008. The Cheshire Building Society branch opposite is being retained and will continue to operate.
The current rateable value of the building on the corner of Castle Street and Churchill Way is £317,500. Colliers has not published a guide price.
Rupert Barron, director of offices at Colliers in Manchester, said the building has planning consent for use as offices but could be converted to accommodate a range of alternative uses such as retail and hotel development. He said: "We're very confident that this impressive building will be of great interest to businesses seeking a purpose-built head office or a centrally-locate building property or prominence that can be adapted to meet their particular requirements."