Spanish fashion retailer Desigual is opening a 5,108 sq ft store at Grosvenor's Liverpool One development in October.
The store is located in Paradise Street, Liverpool city centre, alongside other retailers including G Star, Oakley, Drome, Cult, Apple and Urban Outfitters.
Chris Bliss, Liverpool One estate director, said: "Desigual is a young, very popular brand and a strong addition to Paradise Street and the wider Liverpool One offer. We are thrilled to have a brand of this calibre and stand-out choose Liverpool One for its latest flagship store."
Desigual's only other UK store is based in London.
Cushman & Wakefield and Tushingham Moore acted for Grosvenor, while Desigual represented itself in the letting deal. Details of the rental agreement were not disclosed.
Desigual's headquarters is based in Barcelona, Spain.