Langtree has been chosen by the public sector as the development partner to expand Daresbury Science and Innovation Campus in Halton.
Halton Council, North West Development Agency and the Science & Technology Facilities Council are deliver 1m sq ft over the next 30 years.
Langtree beat British Land, Goodmans, Igloo and Quantum to win the development contract. The original developer, St Modwen, withdrew at the outset of the recession.
John Downes, managing director of Langtree, said: "The Daresbury Science and Innovation Campus is of real regional and national significance and we are proud to have been selected as the joint venture partner to deliver subsequent phases of its development.
"Any development on this scale requires careful handling and our track record of delivering and managing high specification accommodation, while working hand in hand with the public sector, speaks for itself.
"We look forward to bringing the next phases of this development to fruition in the coming months and years."
Prof Colin Whitehouse, chairman of the joint venture executive steering group and deputy chief executive of the Science & Technology Facilities Council, said: "Langtree are very supportive of and committed to the campus vision based on a major expansion of Daresbury as a national and international location for world leading science, technology and innovation."
The NWDA is also investing in a new grow-on building, Vanguard House, which will be completed by Q1 2011. The funding for Vanguard House will take the total NWDA investment on the Campus to over £67m.