Bill's has opened a 3,150 sq ft restaurant in Liverpool ONE, between Chavasse Park and the Hilton Hotel in the former Café Sports Express unit.
The Liverpool ONE site is Bill's first in the city and its second in the North West, with the other in Manchester's John Dalton Street.
In June, Grosvenor reported a record year for Liverpool ONE's restaurants and cafes, with catering sales up 13% on the previous year.
Other new dining additions in 2014 included Ed's Easy Diner, independent coffee house, Home, the first TGI Friday's in Liverpool, and the first Hotel Chocolat Cocoa Café-Bar in the North West.
Miles Dunnett, head of asset management at Grosvenor Liverpool Fund, said: "Bill's is a great new brand for Liverpool ONE. Their breakfast to bedtime offer is perfect for Liverpool ONE, particularly in this location given its proximity to Liverpool ONE's hotels and the wider city centre context. With Liverpool ONE's footfall continuing to grow, and the city holding the position of the fastest growing tourist destination in the UK, Bill's will be a great success."
Cushman & Wakefield and Tushingham Moor acted for Liverpool ONE. Mason Owen represented Bill's.