Cheshire East Council has granted PH Homes full planning permission for 74 homes at Alderley Park.
The PH Homes scheme is the first residential phase of a £160m masterplan for Alderley Park, outlined by owner Manchester Science Partnerships for the former AstraZeneca site.
There will eventually be up to 275 homes, with the new phases sitting alongside the ongoing creation of 410,000 sq ft of science space, in addition to the 1m sq ft already in place.
Following the purchase of 13 acres last year, PH Homes has planned 74 properties ranging from two-bedroom townhouses to six-bedroom villas.
The properties are split into three different developments: The Ride, with detached and semi-detached homes next to a cricket pitch, walled garden and mature trees; Cedar Square, with Georgian-style townhouses and semi-detached properties arranged around a Lebanese Cedar tree, and the Serpentine, with six-bedroom villas, which takes its name from the winding stream running along its southern boundary. The architect is Robert Adam.
Alderley Park also has consent for a gastro-pub, farm shop and sporting facilities including a gym, squash and tennis courts. There is also access to the estate parkland, woodland walks and the original listed walled gardens, arboretum, water garden and stream.
The first homes should be available by early 2018.