Aedas Architects has been appointed to draw up detailed plans for the new bus station in the town centre, which was granted outline consent last week.
Greater Manchester Passenger Transport Executive is spending £48m on the new bus station next to Bolton railway station, on land bounded by Newport Street and Great Moor Street.
The Leeds office of Aedas will handle the work and has been working on the scheme since the start and will see it through to completion.
Nick Bogle, Aedas regional director, said: "We are delighted to continue our long association with GMPTE and look forward to delivering a first class scheme which will enhance Bolton town centre transport provision."
Aedas also designed Hyde bus station and the ground transport interchange at Manchester airport.
The new Bolton bus station will replace the existing facility at Moor Lane and offer improved links between rail and bus services, as well as improved waiting areas, passenger facilities, accessibility, information, and safety and security.
Cllr Richard Knowles, chairman of Greater Manchester Integrated Transport Authority's capital project committee, said: "This project is a very important scheme contributing to Bolton's regeneration and, together with the project to improve Bolton rail station, will make public transport a more attractive and appealing option within the town centre.
"The new facility will be a modern and high quality bus station, so I'm really pleased that we can now press ahead with the project and develop a striking, landmark facility in the town centre that the people of Bolton can be proud of."
The new station is part of the 67-hectare Innovation Zone around the college. It is intended that a detailed planning application will be submitted early next year. Subject to securing the necessary approvals and permissions, the new facility could be operational by winter 2014/2015.